23:28 , Jun 7, 2018 |  BC Innovations  |  Translation in Brief

New Therapeutic Targets and Biomarkers: May 2018

New Therapeutic Targets and Biomarkers: May 2018 Select top therapeutic targets and biomarkers covered by BioCentury or added to the BCIQ database during May 2018. Therapeutic targets are defined as any protein, gene or other molecule...
18:21 , May 23, 2018 |  BC Innovations  |  Distillery Therapeutics

Neurology; musculoskeletal

INDICATION: Amyotrophic lateral sclerosis (ALS); musculoskeletal In vitro, cell culture and fruit fly studies suggest promoting the expression of TNPO1 could help treat ALS caused by FUS mutations and multisystem proteinopathy caused by HNRNPA1 mutations. In...
08:00 , Nov 21, 2013 |  BC Innovations  |  Distillery Therapeutics

Indication: Neurology

This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Neurology Amyotrophic lateral sclerosis (ALS) Chromosome 9 open reading frame 72 (C9orf72) Studies...
08:00 , Nov 7, 2013 |  BC Innovations  |  Cover Story

ALS antisense oligonucleotides

Isis Pharmaceuticals Inc. has teamed up with a trio of academic groups to develop antisense therapeutics for the largest subset of patients with amyotrophic lateral sclerosis,1-3 and all three teams have converged on a common...