07:02 , Jul 17, 2019 |  BC Extra  |  Company News

On heels of trial readout, Frequency out-licenses hearing loss therapy to Astellas

Frequency has found a partner in Astellas for its regenerative therapy to treat hearing loss in a deal that will support development of FX-322 as it moves into Phase IIa testing next quarter. Astellas Pharma...
07:00 , Sep 1, 2016 |  BC Innovations  |  Distillery Therapeutics

Therapeutics: Lipoteichoic acid (LTA); heparin-binding EGF-like growth factor (HBEGF; DTR)

Infectious disease INDICATION: Clostridium Mouse studies suggest LTA glycan-based vaccines could help prevent Clostridium difficile infection (CDI). In a mouse challenge model of CDI, a compound composed of glycans from C. difficile LTA conjugated to...
07:00 , Mar 18, 2013 |  BioCentury  |  Strategy

Japan's biggest biotech

Japanese pharmaceutical companies have historically been thought of as stodgy, insular and opaque, but that is changing fast. One year into the job, Kyowa Hakko Kirin Co. Ltd. 's CEO is building his company along...
07:00 , Jul 29, 2010 |  BC Innovations  |  Targets & Mechanisms

Attacking cancer's secretive side

Researchers from the Weizmann Institute of Science have shown that antibodies against epidermal growth factor receptor ligands from pancreatic tumors boosted the effectiveness of Eli Lilly and Co. 's Gemzar gemcitabine, one of the two...
07:00 , Jul 15, 2010 |  BC Innovations  |  Distillery Therapeutics

Indication: Cancer

Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Pancreatic cancer Transforming growth factor-a (TGFA; TGFa); heparin-binding EGF-like growth factor (HBEGF) Mouse studies suggest that antibodies targeting EGFR ligands could increase the efficacy of...
07:00 , Jun 14, 1999 |  BC Week In Review  |  Clinical News

BioSpecifics, Tufts University regulatory update

The parties jointly received U.S. Patent No. 5,851,522 covering an enzyme formulation consisting of the collagenase enzyme and the hbEGF growth factor as a wound healing agent. BioSpecifics Technologies Corp. (BSTC), Lynbrook, N.Y.   Tufts...