BioCentury | Nov 25, 2020
Product Development

Data Byte: a snapshot of the clinical cutaneous T cell lymphoma pipeline

...Phosphoinositide 3-kinase γPI3Kδ – Phosphoinositide 3-kinase δPNP – Purine nucleoside phosphorylase Danielle Golovin RP6530 resminostat (4SC-201, byk408740) Mundesine (BCX-1777 (oral), forodesine) fenretinide (4-hpr) Quisinostat...
BioCentury | Feb 22, 2010
Company News

Symyx deal

...Symyx said an undisclosed company will acquire its High Productivity Research ( HPR ) business unit..., for a $10 million loan and a 19.5% equity stake in the acquiring company. HPR...
BioCentury | May 18, 2009
Company News

Children's Hospital Los Angeles, John Wayne Cancer Institute, National Institutes of Health cancer news

...the newco an exclusive, worldwide license to IP covering a new formulation of fenretinide (4- HPR...
BioCentury | May 22, 2008
Distillery Therapeutics

This Week in Therapeutics

...sleeping sickness Trypanosoma brucei haptoglobin-hemoglobin receptor (TbHpHbR); haptoglobin-related protein (Hpr; TLF-1); apolipoprotein L1 (ApoL1); haptoglobin-related protein-hemoglobin complex (Hpr-Hb...
...sleeping sickness. In human serum, the TbHpHbR mediated uptake of high-density lipoprotein particles that contained Hpr...
...knockdown conferred parasitic resistance to ApoL1-mediated lysis. Next steps include coupling a toxin to the Hpr-Hb...
BioCentury | Jan 2, 2006
Clinical News

Brecanavir: Interim Phase II data

Interim data from 24-week analysis of an open-label, 48-week Phase II trial (HPR10006) in 31 patients, 81% had plasma HIV-1 RNA below the level of detection of standard assays (<400 copies/mL) and 77% had viral...
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