...AXO-Lenti-PD and ProSavin are each lentiviral gene therapies designed to deliver three genes -- TYH, GCH1...
...was up 3.40p to 713.30p on Monday. Targets: DDC (AADC) - Dopa decarboxylase; GCH1 - GTP cyclohydrolase 1...
...B; TYH - Tyrosine hydroxylase Sandi Wong, Staff Writer AXO-AAV-GM2 AXO-Lenti-PD, OXB-102 Sio Gene Therapies Inc. Dopa decarboxylase (DDC) (AADC) GTP cyclohydrolase 1 (GCH1) Hexosaminidase...

...28-day toxicology study" for one of its lead programs. Quartet was developing inhibitors of GTP cyclohydrolase 1 (GCH1...

...28-day toxicology study" for one of its lead programs. Quartet was developing inhibitors of GTP cyclohydrolase 1 (GCH1...
...31. Koenig is also an advisor at Atlas. Chris Lieu Atlas Venture Merck & Co. Inc. Quartet Medicine Inc. GTP cyclohydrolase 1 (GCH1) Sepiapterin...

...is investigating inhibitors of two key enzymes in the BH4 de novo synthesis pathway: GTP cyclohydrolase 1 (GCH1...
...the final conversion step in the pathway. Pojasek said rat data have shown that inhibiting GCH1...
...on these findings, Quartet raised $17 million in a series A round to get a GCH1...

...Pfizer Venture Investment and Partners Innovation Fund also participated. Quartet is developing inhibitors of GTP cyclohydrolase 1 (GCH1...

...of sepiapterin reductase (SPR) in lead development for neuropathic pain and an inhibitor of GTP cyclohydrolase 1 (GCH1...

...The ideas that PureTech turned into Solace include a preclinical series of GTP cyclohydrolase ( GCH1...
...that modulates glial cells that had completed Phase III testing in another, undisclosed indication. The GCH1...
...Research Group at Massachusetts General Hospital and Harvard Medical School. He discovered that the enzyme GCH1...