BioCentury | Jul 18, 2020
Translation in Brief

Fate licenses rejection-resistant T cell therapies; plus a marker for anti-PD-1 treatment responsiveness, a cell proliferation control switch and more

...ADAM metallopeptidase domain 10 CTLA-4 (CTLA4; CD152) - Cytotoxic T-lymphocyte associated protein 4 GDF15 - Growth differentiation factor...
...death 1 (PD-1) (PDCD1) (CD279) ADAM metallopeptidase domain 10 (ADAM10) Cytotoxic T-lymphocyte associated protein 4 (CTLA-4) (CTLA4) (CD152) Growth differentiation factor...
BioCentury | Jul 16, 2020
Emerging Company Profile

Fountain Therapeutics: an AI-based platform to reverse cellular aging

...issued Danielle Golovin, Staff Writer Fountain Therapeutics Nan Fung Life Sciences Khosla Ventures Alkahest Inc. Elevian Inc. Unity Biotechnology Inc. Juvenescence Ltd. Human Longevity Inc. Growth differentiation factor...
BioCentury | Mar 11, 2020
Product Development

Novo’s year of obesity

...model, achieving plasma levels similar to a subcutaneous injection. Targets GCG - Glucagon GDF15 - Growth differentiation factor...
BioCentury | Dec 19, 2019

Promoting calcium channel signaling in muscle to treat age-related atrophy

...muscle mass and increased muscle force. TARGET/MARKER/PATHWAY: Calcium channel voltage-gated channel β 1 subunit (CACNB1); growth differentiation factor...
...Piétri-Rouxel, same affiliation as above email: Claire Quang Sorbonne University Calcium channel voltage-gated channel beta 1 subunit (CACNB1) growth differentiation factor...
BioCentury | Oct 9, 2019
Company News

CTFH latest to partner with Insilico in AI discovery deal

...other companies this year, including a deal with Elevian Inc. to discover small molecules targeting growth differentiation factor...
BioCentury | Apr 12, 2019
Clinical News

Acceleron discontinues ACE-2494 due to antidrug antibodies

...Targets: MSTN (GDF8) - Myostatin; GDF11 - Growth differentiation factor 11 Brian Moy, Assistant Editor ACE-2494 Acceleron Pharma Inc. Activin A Growth differentiation factor...
BioCentury | Mar 26, 2019
Financial News

NGM could get $975M valuation in NASDAQ IPO

...Fibroblast growth factor 19; FGFR1c - Fibroblast growth factor receptor 1c isoform; GDF15 - Growth differentiation factor...
BioCentury | Mar 22, 2019
Company News

Merck extends discovery partnership with NGM, drops obesity candidate

...Growth differentiation factor 15; KLB - Klotho β Elizabeth S. Eaton, Staff Writer MK-3655 (NGM313) Merck & Co. Inc. NGM Biopharmaceuticals Inc. Growth differentiation factor...
BioCentury | Jan 9, 2019
Company News

Elevian, AI company Insilico partner to find anti-aging candidates in GDF11 pathway

...GDF11 - Growth differentiation factor 11; TGFβ - Transforming growth factor β Elizabeth S. Eaton Elevian Inc. Insilico Medicine Inc. Growth differentiation factor...
BioCentury | Oct 5, 2018
Financial News

New IPO filings include NGM, Arog, Gamida

...Merck & Co. Inc. (NYSE:MRK) giving the pharma exclusive, worldwide rights to its program targeting growth differentiation factor...
...isoform (FGFR1c) Fibroblast growth factor 19 (FGF19) FMS-like tyrosine kinase 3 (FLT3) (CD135) GDNF family receptor alpha like (GFRAL) Growth differentiation factor...
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