08:00 , Feb 5, 2015 |  BC Innovations  |  Distillery Techniques

Techniques: Gremlin 1 (GREM1)-positive osteochondroreticular stem cells

Drug platforms TECHNOLOGY: Cell therapy Cell culture and mouse studies have identified GREM1-positive osteochondroreticular stem cells that could help promote bone repair. In marrow stromal cultures, GREM1-positive stem cells had increased clonogenicity compared with mesenchymal cells. In...
07:00 , Jun 12, 2014 |  BC Innovations  |  Distillery Therapeutics

Indication: Cancer

Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Glioblastoma Gremlin 1 (GREM1) In vitro and mouse studies suggest inhibiting GREM1 could help treat glioblastoma. In...
07:00 , Oct 10, 2013 |  BC Innovations  |  Distillery Therapeutics

Indication: Cardiovascular disease

Indication Target/marker/pathway Summary Licensing status Publication and contact information Cardiovascular disease Atherosclerosis Gremlin 1 (GREM1); macrophage migration inhibitory factor (MIF) In vitro and mouse studies suggest a...
08:00 , Nov 21, 2011 |  BC Week In Review  |  Clinical News

ConfirmMDx for Lung Cancer diagnostic data

Data from sputum samples from 40 NSCLC patients and 52 symptomatic, cancer-free controls showed that using methylation specific PCR to screen for the methylated Ras association domain family 1A (RASSF1A) gene produced 60% sensitivity...