BC Extra | Oct 27, 2017
Preclinical News

Cell study points to new antibiotic strategy

A study in Cell shows granzyme B (GrB; GZMB), an immune cell protease, kills diverse bacterial species by shutting down multiple conserved survival pathways. The authors suggest compounds that mimic the protease’s mechanism could treat...
BC Innovations | Dec 18, 2008
Distillery Therapeutics

This week in therapeutics

The Distillery: Therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Dermatology Dermal ulcers Granulysin In vitro and mouse studies suggest that targeting granulysin could help treat the skin disease Stevens-Johnson syndrome (SJS) and...
BC Innovations | Dec 18, 2008
Targets & Mechanisms

Granulysin skin game

Researchers in Taiwan have identified a cytotoxic protein, granulysin, that could be targeted to treat or diagnose Stevens-Johnson syndrome and toxic epidermal necrosis. 1 The data suggest the protein is a central player in the...
BC Week In Review | Feb 5, 2001
Company News

University of California other research news

Researchers published in Nature Medicine that granulysin, a peptide released by T cells, contributes to host defense against bacterial, fungal and parasitic pathogens, including Mycobacterium leprae, which causes leprosy. University of California, Los Angeles, Calif....
Items per page:
1 - 4 of 4