03:19 , Nov 2, 2018 |  BC Innovations  |  Targets & Mechanisms

FDA’s pediatric target picks

FDA is looking ahead of industry in its guideline on targets for pediatric oncology, which includes more than 50 not yet in company pipelines in a list of over 220 the agency has its eye...
21:06 , Sep 21, 2017 |  BC Innovations  |  Translation in Brief

Driving CARs into neuroblastoma

In separate studies published in the same July issue of the Proceedings of the National Academies of Sciences , NCI and Karolinska Institute teams each discovered a new target for high-risk forms of neuroblastoma. The...
17:07 , Sep 13, 2017 |  BC Innovations  |  Distillery Therapeutics

Cancer

INDICATION: Neuroendocrine tumors Patient sample, cell culture and mouse studies suggest immunotherapies targeting GPC2 could help treat neuroblastomas expressing the antigen. In neuroblastoma patients, high levels of GPC2 in tumor samples correlated with poor overall...
00:28 , Mar 31, 2017 |  BC Innovations  |  Targets & Mechanisms

Cells on the rise

This year’s meeting of the American Association for Cancer Research (AACR) will keep the spotlight on immuno-oncology, where preclinical science is continuing to expand the use of different types of innate and adaptive immune cells...