BioCentury | Apr 20, 2017
Product R&D

Selectivity suite

Although the small molecule landscape has been largely defined by protein-binding agents, new classes of compounds are emerging that block the formation of specific proteins at the level of their RNA, redefining what constitutes a...
BioCentury | Jun 19, 2014
Distillery Therapeutics

Indication: Endocrine/metabolic disease

...Publication and contact information Endocrine/metabolic disease Diabetes Glycerol-3-phosphate dehydrogenase 2 mitochondrial (GPD2) Rodent and in vitro studies suggest inhibiting GPD2...
...shuttle enzyme GPD2. In rats and mice, an antisense oligonucleotide targeting Gpd2 or knockout of Gpd2...
...glucose homeostasis, endogenous glucose production and cellular redox state. Next steps could include developing pharmacological GPD2...
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