BioCentury | Sep 22, 2011
Distillery Therapeutics

Indication: Cancer

...status Publication and contact information Cancer Cancer Glutathione S-transferase w1 (GSTO1) In vitro studies identified GSTO1...
...compound selectively inhibited GSTO1 with an IC50 of 35 nM. In the same cells, the GSTO1...
...Next steps include determining whether the compound selectivity inhibits GSTO1 in vivo and whether inhibiting GSTO1...
BioCentury | Apr 16, 2009
Cover Story

Probing the character of proteins

...implicated in human cancers: retinoblastoma binding protein 9 (RBBP9) and glutathione S -transferase w1 ( GSTO1...
...that inhibited the protein at low micromolar concentrations. A screen of a 2,000-member library against GSTO1...
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