04:50 , Nov 30, 2018 |  BC Innovations  |  Targets & Mechanisms

Revving up metabolism at ASH 2018

Cancer metabolism is a prominent theme at this year’s ASH meeting, with researchers broadening the tent from metabolic targets that drive hematologic malignancies to those that intersect with other hot topics, notably immuno-oncology and epigenetics....
08:00 , Nov 21, 2013 |  BC Innovations  |  Distillery Therapeutics

Indication: Cancer

This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Acute myelogenous leukemia (AML) Glutamate-cysteine ligase catalytic subunit (GCLC); glutathione peroxidase 1 (GPX1) In vitro studies suggest inhibiting glutathione metabolism could...
07:00 , Sep 26, 2013 |  BC Innovations  |  Distillery Therapeutics

Indication: Neurology

This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Neurology Huntington's disease Glutathione peroxidase 1 (GPX1); glutathione peroxidase 3 plasma (GPX3) Yeast and fly studies suggest glutathione peroxidase mimics could be...
07:00 , Oct 15, 2009 |  BC Innovations  |  Distillery Therapeutics

Indication: Endocrine disease

Indication Target/marker/pathway Summary Licensing status Publication and contact information Endocrine disease Diabetes Glutathione peroxidase 1 (GPX1) In vitro and mouse studies suggest that GPX1 inhibitors could help prevent type 2 diabetes. In mouse embryonic fibroblasts,...