...Staff Writer Otonomy’s negative Phase III readout calls into question the utility of targeting the glucocorticoid receptor...
...and hearing loss.Otonomy Inc. (NASDAQ:OTIC) announced Monday that Otividex, its sustained-release dexamethasone gel, which targets GCCR, missed...
...differentiation from placebo in definitive vertigo days during month three. Adare Pharma Solutions has a sustained-release GCCR-targeted...

...agonist abediterol for asthma and chronic obstructive pulmonary disease (COPD); and Phase II development of GCCR...

...DISEASE CATEGORY: CancerINDICATION: Melanoma; colorectal cancerInhibiting the glucocorticoid receptor could...
...translational studies in multiple, undisclosed cancer types.TARGET/MARKER/PATHWAY: Glucocorticoid receptor (GCCR...
...and Harvard Harvard Medical School Brigham and Women's Hospital Glucocorticoid receptor (GCCR) Interleukin-27(IL-27...

...raised $75 million at a valuation of $394.4 million. ORIC’s lead program, ORIC-101, is a GCCR...
...Seragon Pharmaceuticals, each of which was acquired by a large pharma, ORIC’s team has implicated GCCR...
...an exercise price of $11.50 per whole share. Targets CD73 (NT5E) - Ecto-5’-nucleotidase GCCR - Glucocorticoid receptor Paul...

...$75 million and value ORIC at $394.4 million. The company’s lead program, ORIC-101, is a GCCR...

...the Weizmann Institute showed that GCCR inhibitors could be repurposed to treat Ewing sarcoma. The GCCR...
...in mice with metastatic Ewing sarcoma. Laboratoires Exelgyn markets Mifegyne for Cushing syndrome. TARGET/MARKER/PATHWAY: Glucocorticoid receptor (GCCR...
...CONTACT: Yosef Yarden, Weizmann Institute of Science, Rehovot, Israel email: yosef.yarden@weizmann.ac.il Claire Quang Weizmann Institute of Science Glucocorticoid receptor (GCCR...

...years of runway. ORIC's lead compound is based on research from Sawyers' lab, which implicated GCCR...
...series D will support a new Phase Ib trial slated for 3Q19 to evaluate the GCCR...
...an IPO was in the company’s near-term plans. Targets: CD73 (NT5E) - Ecto-5’-nucleotidase; GCCR - Glucocorticoid receptor Elizabeth...

...DISEASE CATEGORY: Inflammation INDICATION: Asthma In vitro and mouse studies identified a glucocorticoid ligand of GCCR...
...preclinical PK/PD, toxicity and safety studies. GlaxoSmithKline plc markets Arnuity Ellipta for asthma. TARGET/MARKER/PATHWAY: Glucocorticoid receptor (GCCR...
...Rapids, Mich. email: eric.xu@vai.org Claire Quang Chinese Academy of Sciences Cleveland Clinic Foundation Harbin Institute of Technology Van Andel Institute Glucocorticoid receptor (GCCR) Asthma...

...Clearside Biomedical Inc. (NASDAQ:CLSD), Alpharetta, Ga. Product: Xipere (formerly CLS-TA) Business: Ophthalmic Molecular target: Glucocorticoid receptor (GCCR...
...at six months Status: Development discontinued Milestone: NA Brian Moy Zuprata (CLS-1001, CLS-TA, CLS 1001) Clearside Biomedical Inc. Glucocorticoid receptor (GCCR) Xipere...

...method identified correlations between high RNA expression and promoter accessibility for 130 genes, including the glucocorticoid receptor...