07:00 , May 26, 2016 |  BC Innovations  |  Distillery Therapeutics

Therapeutics: GLI family zinc finger 1 (GLI1); GLI3; suppressor of fused homolog (SUFU)

Hepatic disease INDICATION: Hepatic Mouse and cell culture studies suggest promoting expression of GLI1 and GLI3 or inhibiting SUFU could help treat hepatic steatosis. Hepatocyte levels of GLI1 and GLI3 were lower in three mouse...
07:00 , May 29, 2008 |  BC Innovations  |  Distillery Therapeutics

This Week in Therapeutics

This week in therapeutics Indication Target/marker/ pathway Summary Licensing status Publication and contact information Musculoskeletal disease Osteoporosis Hedgehog (Hh); Patched1 (Ptch1); GLI-Kruppel family member 3 (Gli3); Gli2; repressor form of Gli3 (Gli3rep) A mouse study...