...generic TOP1 inhibitor camptothecin linked to neutrally charged γ-glutamyl polymers that are converted by tumor-expressed GGT...
...mouse model of pancreatic cancer, the conjugate prevented tumor relapse and extended survival. TARGET/MARKER/PATHWAY: ϒ-glutamyltransferase (GGT...
...email: guzhen@ucla.edu CONTACT: Youqing Shen, Zhejiang University, Hangzhou, China email: shenyq@zju.edu.cn Inhua Muijrers-Chen Heredity pancreatic cancer panel ZenCapsule Inc. Gamma-glutamyltransferase (GGT) Topoisomerase...

...twice-daily 400 mg dose group met the primary endpoint of reduction in γ glutamyl transpeptidase (GGT...

...high dose of seladelpar vs. 8.9% for placebo (p<0.0001), and 43.1% for gamma glutamyl transferase (GGT...

...showing that twice-daily GKT831 led to a significant 23% reduction in mean γ glutamyl transpeptidase (GGT...
...primary endpoint of the trial is evaluating the change from baseline to week 24 in GGT...
...inhibitor Indication: Treat primary biliary cholangitis (PBC) Endpoint: Change from baseline in γ glutamyl transpeptidase (GGT...

...showing that twice-daily GKT831 led to a significant 23% reduction in mean γ glutamyl transpeptidase (GGT...
...primary endpoint of the trial is evaluating the change from baseline to week 24 in GGT...

...in the trial, which is enrolling about 12 patients. Two patients had elevated gamma-glutamyl transferase (GGT...

...in the trial, which is enrolling about 12 patients. Two patients had elevated gamma-glutamyl transferase (GGT...

...alkaline phosphatase, total bilirubin, direct bilirubin, alanine aminotransferase (ALT), aspartate aminotransferase (AST) and gamma-glutamyl transferase (GGT...

...phosphatase levels at week 8 and safety; aspartate aminotransferase (AST), alanine aminotransferase (ALT), gamma-glutamyl transferase (GGT...

...and safety. Secondary endpoints include measurements of aspartate aminotransferase (AST), alanine aminotransferase (ALT), gamma-glutamyl transferase (GGT...
...phosphatase levels at week 8 and safety; aspartate aminotransferase (AST), alanine aminotransferase (ALT), gamma-glutamyl transferase (GGT...