18:08 , Jul 10, 2017 |  BC Innovations  |  Distillery Techniques

Biomarkers

TECHNOLOGY: Gene profiling A 10-gene signature in tumors could help predict survival in breast cancer. In 4,994 breast cancer patients, low tumors levels of a signature based on the expression of 10 genes -- including...
07:00 , Mar 26, 2015 |  BC Innovations  |  Distillery Therapeutics

Therapeutics: GATA binding protein 2 (GATA2); insulin-like growth factor-2 (IGF-2)

Cancer INDICATION: Prostate cancer In vitro and mouse studies suggest inhibiting GATA2- IGF2 signaling could resensitize prostate cancer to chemotherapy. In chemotherapy-resistant human prostate cancer cells, levels of the transcription factor GATA2 and its target...
08:00 , Mar 5, 2009 |  BC Innovations  |  Distillery Therapeutics

Indication: Various

This week in therapeutics Indication Target/marker/ pathway Summary Licensing status Publication and contact information Various Macular degeneration; diabetic retinopathy; cancer; arthritis; psoriasis Vascular endothelial growth factor receptor 2 (KDR; FLK-1; VEGFR2); glucocorticoid receptor DNA binding...