BioCentury | Feb 5, 2020
Product Development

2019-nCoV drug discovery: HHS funds Regeneron mAbs and BenevolentAI deploys machine learning

...Eli Lilly and Co. (NYSE:LLY) and Incyte Corp. (NASDAQ:INCY). BenevolentAI’s platform also predicted Olumiant binds GAK... Targets AAK1 - AP2 associated kinase 1 ACE2 - Angiotensin-converting enzyme 2 GAK - Cyclin G associated kinase (GAK)...
BioCentury | Apr 30, 2015
Distillery Therapeutics

Therapeutics: Cyclin G associated kinase (GAK)

...Infectious disease INDICATION: Hepatitis C virus (HCV) In vitro studies suggest isothiazolo[5,4-b]pyridine-based GAK inhibitors could help... treat HCV infection. Two lead isothiazolo[5,4-b]pyridine analogs from a small molecule library screen bound GAK's...
...toxicity. Next steps include improving the drug properties of the two lead GAK inhibitors. TARGET/MARKER/PATHWAY: Cyclin G associated kinase (GAK)...
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