BioCentury | Oct 24, 2013
Distillery Therapeutics

Indication: Endocrine/metabolic disease

...and contact information Endocrine/metabolic disease Metabolic disease G protein-coupled receptor 171 (GPR171) Cell culture and mouse studies suggest modulating GPR171...
...BigLEN was shown to bind and activate GPR171. In mice, small hairpin RNA knockdown of Gpr171...
...food intake compared with no knockdown. Next steps include screening for agonists and antagonists of GPR171...
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