BioCentury | Oct 16, 2014
Distillery Therapeutics

Indication: Cancer

...Cancer G protein-coupled receptor 126 (GPR126); VEGF receptor 2 (KDR/Flk-1; VEGFR-2) In vitro, mouse and zebrafish studies suggest inhibiting GPR126...
...shRNA against Gpr126 decreased pathogenic vessel formation compared with control shRNA. In zebrafish, morpholinos targeting gpr126...
...inhibited vessel outgrowth, whereas a control morpholino did not. In human endothelial cells, shRNA against GPR126...
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