08:00 , Feb 28, 2013 |  BC Innovations  |  Targets & Mechanisms

Making TRAIL

Researchers at the Penn State Milton S. Hershey Medical Center have identified a small molecule inducer of TRAIL expression that has antitumor effects in multiple mouse models.1Oncoceutics Inc. has licensed the findings and plans to...
07:00 , May 31, 2012 |  BC Innovations  |  Distillery Therapeutics

Indication: Cancer

Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Colorectal cancer b-Catenin (CTNNB1); forkhead box O3 (FOXO3; FOXO3a); phosphoinositide 3-kinase (PI3K); protein kinase B (PKB; PKBA; AKT;...
08:00 , Feb 18, 2010 |  BC Innovations  |  Targets & Mechanisms

Turning up the heat on HD

Researchers at Duke University have found small molecules that help cells untangle aggregates of the misfolded protein thought to cause Huntington's disease.1 The molecules are now the lead compounds for Chaperone Therapeutics Inc., a neurology...
07:00 , Aug 27, 2009 |  BC Innovations  |  Distillery Therapeutics

Indication: Cardiovascular disease

Indication Target/marker/pathway Summary Licensing status Publication and contact nformation Cardiovascular disease Cardiac hypertrophy Sirtuin...
07:00 , Jul 9, 2009 |  BC Innovations  |  Distillery Therapeutics

Indication: Neurology

Indication Target/marker/pathway Summary Licensing status Publication and contact information Neurology Neurology Forkhead box O3...