08:00 , Feb 11, 2016 |  BC Innovations  |  Translation in Brief

The gut of heart disease

Researchers at the Cleveland Clinic have shown that a compound found in red wine, olive oil and other food products could help treat atherosclerosis by inhibiting an early step in the biosynthesis of trimethylamine N-oxide...
07:00 , May 14, 2015 |  BC Innovations  |  Distillery Therapeutics

Therapeutics: Flavin containing monooxygenase 3 (FMO3)

Cardiovascular disease INDICATION: Atherosclerosis In vitro, mouse and patient sample studies suggest inhibiting FMO3 could help prevent or treat diabetes-associated atherosclerosis. Liver levels of FMO3 were higher in diabetes patients and several mouse models of...