07:00 , Aug 13, 2015 |  BC Innovations  |  Distillery Therapeutics

Therapeutics: FK506 binding protein 1B 1 (FKBP1B; calstabin-2)

Neurology INDICATION: Cognitive dysfunction Rat studies suggest FKBP1B could help treat age-related cognitive dysfunction. In aged rats, vector-mediated expression of FKBP1B in the hippocampus decreased calcium-dependent potassium currents and increased spatial memory function to levels comparable to...
07:00 , Sep 20, 2012 |  BC Innovations  |  Targets & Mechanisms

Stabilizing RyR2

A group at Columbia University has found that preventing the leak of calcium ions from ryanodine receptors could help treat post-traumatic stress disorder, and a French team has found that the strategy could be effective...