BioCentury | Aug 26, 2019
Product Development

Vax to the future: How Anthony Fauci is thinking about next-gen vaccines and other NIAID priorities

...NIH launched a clinical trial of its own structure-guided universal flu candidate, H1ssF_3928 -- a ferritin...
BioCentury | Apr 5, 2019
Clinical News

NIH begins universal flu vaccine trial

...the first five subjects and 60 μg in the remaining participants. The vaccine comprises non-human ferritin...
...virus hemagglutinin (HA) stem, a highly conserved HA domain, from the H1N1 strain. Sandi Wong, Staff Writer NIH Ferritin Influenza...
BioCentury | Jul 13, 2018
Clinical News

Acceleron, Celgene score second win with latest luspatercept readout

...burden, mean change in transfusion burden, liver iron concentration, daily iron chelation therapy dose, serum ferritin...
BioCentury | Jan 4, 2018
Translation in Brief

New Therapeutic Targets and Biomarkers: December 2017

...News Cancer Archaeoglobus fulgidus ferritin ( A. fulgidus ferritin) In vitro studies suggest A. fulgidus ferritin-based...
BioCentury | Dec 19, 2017
Distillery Techniques

Drug delivery

...TECHNOLOGY: Nanoparticles Nanoparticles based on A. fulgidus ferritin could deliver thermally and/or chemically labile proteins to...
...animal models of cancer. DESCRIPTION: Protein-based nanoparticles composed of Archaeoglobus fulgidus ferritin ( A. fulgidus ferritin...
...University of Singapore, Singapore email: mdccld@nus.edu.sg Karen Tkach Tuzman National University of Singapore Archaeoglobus fulgidus ferritin (A. fulgidus ferritin...
BioCentury | Jul 27, 2017
Translation in Brief

Sepsis' sweet tooth

...hepatocyte and liver macrophage ferritin levels increased after sepsis induction in mice. Conditional knockout of ferritin...
...Adenoviral vector-mediated overexpression of ferritin heavy polypeptide 1 (FTH1) -- which encodes a subunit of ferritin...
...mice, ferritin increased glucose levels and protected the septic mice from death, whereas deletion of ferritin...
BioCentury | Jul 18, 2017
Distillery Therapeutics

Infectious disease

...INDICATION: Sepsis Mouse studies suggest ferritin or promoting FTH1 expression could help treat sepsis. In a...
...and puncture (CLP)-induced sepsis, adenoviral-mediated overexpression of FTH1 in the liver or IV injection of ferritin...
...the effect of heme on iron-regulated glucose production in malaria and other infections. TARGET/MARKER/PATHWAY: Ferritin; ferritin...
BioCentury | Jun 22, 2017
Clinical News

Acceleron, Celgene complete enrollment in Phase III of luspatercept in beta-thalassemia

...burden, mean change in transfusion burden, liver iron concentration, daily iron chelation therapy dose, serum ferritin...
...burden, mean change in transfusion burden, liver iron concentration, daily iron chelation therapy dose, serum ferritin...
BioCentury | Jun 22, 2017
Clinical News

Acceleron, Celgene complete enrollment in Phase III of luspatercept in MDS

...improvement and mean hemoglobin increase, time to and duration of transfusion independence, change in serum ferritin...
...improvement and mean hemoglobin increase, time to and duration of transfusion independence, change in serum ferritin...
BioCentury | Jan 11, 2017
Clinical News

Ferritin IVD Capsule test regulatory update

...Abionic received CE mark approval for its Ferritin IVD Capsule test to diagnose iron deficiency. The...
...iron deficiency. The company plans to launch the product early this year. The test measures ferritin...
...abioSCOPE instrument. Abionic S.A. , Lausanne, Switzerland Product: Ferritin IVD Capsule test Business: Diagnostic Julian Zhu Abionic S.A. Ferritin...
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