18:03 , Mar 13, 2019 |  BC Innovations  |  Distillery Therapeutics

Inhibiting FERMT2 for lung cancer

DISEASE CATEGORY: Cancer INDICATION: Lung cancer Patient sample, cell culture and mouse studies suggest inhibiting FERMT2 could help treat lung cancer. In patient tissue samples, FERMT2 levels were higher in tumor samples than in adjacent...
21:34 , Aug 3, 2017 |  BC Innovations  |  Translation in Brief

New Therapeutic Targets and Biomarkers: July 2017

New Therapeutic Targets and Biomarkers: July 2017 Select top therapeutic targets and biomarkers covered by BioCentury or added to the BCIQ database during July 2017. Therapeutic targets are defined as any protein, gene or other...
23:46 , Jul 13, 2017 |  BC Extra  |  Preclinical News

FERMT2 identified as potential breast cancer target

In a paper published in Cancer Research , researchers at the Cleveland Clinic showed that integrin protein fermitin family member 2 (FERMT2; KIND2) promotes recruitment and subversion of host macrophages, thereby accelerating metastatic progression of...