BioCentury | Oct 5, 2018
Financial News

Owlstone adds $35M to $50M series C

Early disease detection and precision medicine company Owlstone Medical Ltd. (Cambridge, U.K.) raised $35 million led by Horizons Ventures as part of its untranched series C round. The sum brings the total in the round...
BioCentury | Dec 8, 2017
Clinical News

DBV's peanut allergy therapy meets Phase III safety endpoint

DBV Technologies S.A. (Euronext:DBV; NASDAQ:DBVT) said Viaskin Peanut (DBV-712) met the primary safety endpoint in the Phase III REALISE trial to treat peanut allergy in patients ages 4-11. Specifically, Viaskin Peanut was well tolerated with...
BioCentury | Dec 4, 2014
Distillery Therapeutics

Indication: Cancer

...and mouse studies suggest IgM-based conjugates targeting FAIM3 could help treat CLL. The IgM receptor FAIM3...
BioCentury | Feb 6, 2014
Distillery Therapeutics

Indication: Neurology

...information Neurology Multiple sclerosis (MS) Fas apoptotic inhibitory molecule 3 (FAIM3; TOSO) Mouse studies suggest inhibiting the surface receptor TOSO...
...immune-suppressive T helper cells compared with mice expressing normal Toso levels. In the model, a Toso-Fc...
...prior to treatment. Next steps could include identifying a relevant TOSO ligand and developing a TOSO-directed...
BioCentury | Dec 8, 2011
Targets & Mechanisms

Xa and IX mark the clot

...Frankfurt, Germany e-mail: j.schuettrumpf@blutspende.de 3. Bunce, M.W. et al. Blood 117 , 290-298 (2011) 4. Toso...
BioCentury | Jan 27, 2011
Distillery Therapeutics

Indication: Neurology

Indication Target/marker/pathway Summary Licensing status Publication and contact information Neurology Stroke Fas apoptotic inhibitory molecule 2 (FAIM2) Studies in mice suggest that increasing FAIM2 expression could decrease damage resulting from brain ischemia. In a mouse...
BioCentury | Aug 28, 2008
Cover Story

Armed & Dangerous

...4827-4834 (2005) 5. Pawelek, J. et al. Cancer Res. 57 , 4537-4544 (1997) 6. Toso...
BioCentury | Apr 27, 1998
Company News

Rigel Inc. other research news

...Rigel researchers and colleagues published in Immunity the identification of toso, an integral membrane protein expressed...
...cells mediated by Fas and members of the TNF receptor family. The researchers suggested that toso...
...to induce apoptosis of T cells in autoimmune diseases or transplantation. They also suggested that toso...
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