BioCentury | May 21, 2020
Product Development

May 20 Quick Takes: Filgotinib meets in ulcerative colitis; broader labels for Lynparza, Tecentriq, plus updates from Eiger, eGenesis and more

...progeria and progeroid laminopathies, both ultra-rare pediatric diseases. The PDUFA date is Nov. 20. The farnesyl transferase...
BioCentury | Nov 1, 2019
Clinical News

Hepatitis D draft guidance outlines surrogate endpoints

...are due Jan. 1. Therapies in Phase III testing for HDV are Sarasar lonafarnib, a farnesyl transferase...
BioCentury | Sep 3, 2019
Clinical News

Sept. 3 Clinical Quick Takes: Phase II failure for Aridis, plus Kura, Idorsia, Concert, PegBio

...endpoint. Among 13 evaluable patients in the study, which has not yet completed enrollment, the farnesyl transferase...
BioCentury | Oct 26, 2018
Financial News

Eiger prices $43.4M follow-on

...premature aging disease (see "Eiger to Seek FDA Approval of Progeria Therapy" ). Lonafarnib, a farnesyl transferase...
BioCentury | Sep 4, 2018
Company News

Eiger to seek FDA approval of progeria therapy

...does not expect to conduct additional clinical efficacy studies prior to the submission. Lonafarnib, a farnesyl transferase...
BioCentury | Jun 29, 2018
Financial News

Kura, Zafgen price follow-ons

...SCCHN, which it believes could be registrational based on discussions with regulators. Tipifarnib is a farnesyl transferase...
...NASDAQ:KURA), San Diego, Calif. Zafgen Inc. (NASDAQ:ZFGN), Boston, Mass. Jaime De Leon tipifarnib (zarnestra, R115777) ZGN-1061 Kura Oncology Inc. Zafgen Inc. Farnesyl transferase Methionine...
BioCentury | Jun 28, 2018
Financial News

Kura, Zafgen price follow-ons

...SCCHN, which it believes could be registrational based on discussions with regulators. Tipifarnib is a farnesyl transferase...
...ZGN-1061 is a second-generation methionine aminopeptidase 2 (MetAP2) inhibitor. Jaime De Leon tipifarnib (zarnestra, R115777) ZGN-1061 Kura Oncology Inc. Zafgen Inc. Farnesyl transferase Methionine...
BioCentury | May 9, 2018
Distillery Therapeutics

Cancer

...INDICATION: Cancer Cell culture and mouse studies suggest farnesyl transferase inhibitors plus the oncolytic alphavirus M1 could...
...cancers. In a human colorectal cancer cell line treated with alphavirus M1, co-treatment with the farnesyl transferase...
...hepatitis D virus (HDV) infection. Merck & Co. Inc. and Eiger have Sarasar lonafarnib, a farnesyl transferase...
BioCentury | Feb 16, 2018
Clinical News

Kura reports additional Phase II data for tipifarnib in SCCHN

...myelodysplastic syndromes (MDS) and chronic myelomonocytic leukemia (CMML). Kura has exclusive, worldwide rights to the farnesyl transferase...
...Johnson & Johnson (NYSE:JNJ), New Brunswick, N.J. Product: Tipifarnib Business: Cancer Molecular target: Farnesyl transferase Description: Farnesyl transferase...
...Status: Updated Phase II data Milestone: Start Phase III data (2018) Brian Moy tipifarnib Johnson & Johnson Kura Oncology Inc. Farnesyl transferase...
BioCentury | Feb 2, 2018
Financial News

Kura raises $59.1M in an at-the-market financing

...ORR) of 33% (see BioCentury, Jan. 5 ). Kura has exclusive, worldwide rights to the farnesyl transferase...
...BioCentury, March 16, 2015 ). Kura Oncology Inc. (NASDAQ:KURA), La Jolla, Calif. Elizabeth S. Eaton tipifarnib Kura Oncology Inc. Farnesyl transferase...
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