BioCentury | Aug 30, 2019
Translation in Brief

DNA trumps protein in Huntington onset

...stem (iPS) cells and postmortem brain tissues, and is open to partnerships. Targets: FAN1 - FANCD2...
BioCentury | Oct 4, 2018
Distillery Therapeutics

Hematology

...HSPCs). In FANCD2-deficient mouse HSPCs, SH2B3 knockout increased growth compared with normal SH2B3 expression. In FANCD2-deficient...
...inhibitors in models of FANCD2-deficient Fanconi anemia. TARGET/MARKER/PATHWAY: SH2B adaptor protein 3 (SH2B3; LNK); Fanconi anemia complementation group D2 (FANCD2...
...CONTACT: Wei Tong, Children′s Hospital of Philadelphia, Philadelphia, Pa. email: tongw@email.chop.edu Claire Quang Children's Hospital of Philadelphia Fanconi anemia complementation group D2 (FANCD2) SH2B...
BioCentury | Jun 11, 2009
Distillery Therapeutics

Indication: Hematology

...Summary Licensing status Publication and contact information Hematology Anemia Fanconi anemia complementation group A (FANCA); FANCD2...
...human cells suggest that induced pluripotent stem (iPS) cells carrying wild-type versions of FANCA or FANCD2...
...reprogram somatic cells to a pluripotent state. Reprogrammed cells that also expressed normal FANCA or FANCD2...
BioCentury | Jan 5, 2009
Clinical News

Biomarker Panels diagnostic data

...enrolled in a U.S. trial showed that a panel of 4 DNA repair proteins (XPF, FANCD2...
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