BioCentury | Sep 19, 2013
Distillery Therapeutics

Indication: Infectious disease

...Licensing status Publication and contact information Infectious disease SARS-associated coronavirus Exoribonuclease in nonstructural protein 14 (nsp14-ExoN) In vitro studies suggest nsp14-ExoN...
...mutagen therapeutics including ribavirin. In murine hepatitis virus coronaviruses, knockout of the RNA proofreading gene nsp14-ExoN...
...to 5-fluorouracil and ribavirin by 300-fold and decreased viral replication compared with no knockout. In nsp14-ExoN-deficient...
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