08:00 , Dec 13, 2012 |  BC Innovations  |  Cover Story

Translating autism

Researchers at McGill University have mouse data showing a causal link between eIF4E -mediated translational dysregulation and autism-related deficits. The group also corrected the dysregulation-and the associated autistic phenotype-with a small molecule. 1 The McGill...
08:00 , Dec 6, 2012 |  BC Innovations  |  Distillery Therapeutics

Indication: Neurology

Indication Target/marker/pathway Summary Licensing status Publication and contact information Neurology Autism Eukaryotic translation initiation factor 4E (eIF4E); eIF4E binding protein 2 (eIF4EBP2) Mouse studies suggest inhibition of eIF4E signaling could help treat autism spectrum disorder...
07:00 , Jun 19, 2006 |  BioCentury  |  Product Development

Showcasing new diabetes targets

While much of the attention at last week’s American Diabetes Association meeting was focused on late-stage products targeting DPP-4 and GLP-1, companies also presented early data on new targets, including adiponectin receptor 2 and eukaryotic...