BioCentury | Jun 7, 2018
Clinical News

Exact HCC assay significantly better than SOC

...six methylated DNA markers: homeobox A1 (HOXA1); empty spiracles homeobox 1 (EMX1); DNA locus AK055957; endothelin converting enzyme 1 (ECE1)...
...Business: Diagnostic Molecular target: Homeobox A1 (HOXA1); empty spiracles homeobox 1 (EMX1); DNA locus AK055957; endothelin converting enzyme 1 (ECE1)...
...Informal), Cologuard (Other) Exact Sciences Corp. C-type lectin domain family 11 member A (CLEC11A) Empty spiracles homeobox 1 (EMX1) Endothelin converting enzyme 1 (ECE1) Homeobox...
BioCentury | Jun 6, 2018
Product Development

Second (Ex)act

...the Phase II trial: homeobox A1 (HOXA1), empty spiracles homeobox 1 (EMX1), DNA locus AK055957, endothelin converting enzyme 1 (ECE1)...
BioCentury | Jun 5, 2018
Clinical News

Exact HCC assay significantly better than SOC

...six methylated DNA markers: homeobox A1 (HOXA1); empty spiracles homeobox 1 (EMX1); DNA locus AK055957; endothelin converting enzyme 1 (ECE1)...
...Informal), Cologuard (Other) Exact Sciences Corp. C-type lectin domain family 11 member A (CLEC11A) Empty spiracles homeobox 1 (EMX1) Endothelin converting enzyme 1 (ECE1) Homeobox...
BioCentury | Jun 19, 2014
Distillery Therapeutics

Indication: Dermatology

...Licensing status Publication and contact information Dermatology Itch Endothelin 1 (EDN1; ET1); endothelin A receptor; endothelin converting enzyme 1 (ECE1)...
...dermatitis and patients with the pruritic skin disorder prurigo nodularis, endothelin A receptor, ET1 and ECE1...
BioCentury | Jan 14, 2013
Clinical News

CG400549: Phase IIa data

Top-line data from an open-label Phase IIa trial in patients with cABSSSI due to methicillin-resistant Staphylococcus aureus (MRSA) showed that 90.9% of patients receiving once-daily CG400549 for 10-14 days were stable or improving as determined...
BioCentury | Oct 21, 2010
Distillery Therapeutics

Indication: Cancer

Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Interferon-g (IFNG; IFN-g) Mouse studies suggest that inhibiting IFN-g could help increase the efficacy of cancer vaccines. In Ifn-g-/- mice with subcutaneous melanoma tumors,...
BioCentury | Nov 19, 2009
Distillery Therapeutics

Indication: Cardiovascular disease

...Indication Target/marker/pathway Summary Licensing status Publication and contact information Cardiovascular disease Hypertension Angiotensin-converting enzyme (ACE); endothelin converting enzyme 1 (ECE1)...
...neutral endopeptidase (MME; NEP; CD10) In vitro and rat studies suggest that dual ACE and ECE1...
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