BioCentury | Mar 25, 2019
Distillery Therapeutics

Inhibiting EFR3A to treat Alzheimer's disease

...DISEASE CATEGORY: Neurology INDICATION: Alzheimer's disease (AD) Mouse studies suggest inhibiting EFR3A could help treat AD...
...model of AD expressing mutant human amyloid precursor protein (APP) and presenilin 1 (PSEN1; PS1), EFR3A...
...steps could include identifying EFR3A inhibitors and testing them in animal models of AD. TARGET/MARKER/PATHWAY: EFR3 homolog A (EFR3A)...
BioCentury | Jun 29, 2017
Translation in Brief

New Therapeutic Targets and Biomarkers: June 2017

...patients. Canbex Therapeutics Ltd. Pipeline Information Neurology Alzheimer's disease EFR3 homolog A (EFR3A) Fruit fly studies suggest inhibiting EFR3A...
BioCentury | Jun 27, 2017
Distillery Therapeutics

Neurology

...INDICATION: Alzheimer's disease (AD) Fruit fly studies suggest inhibiting EFR3A or PI4KA could help treat AD...
...treat AD. In a Drosophila model of AD, knockout of the fruit fly homolog of EFR3A...
...Next steps could include testing EFR3A and PI4KA inhibition in mouse models of AD. TARGET/MARKER/PATHWAY: EFR3 homolog A (EFR3A)...
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