19:09 , Jan 18, 2017 |  BC Innovations  |  Distillery Therapeutics

Autoimmune disease

INDICATION: Inflammatory bowel disease (IBD); Crohn’s disease Patient sample and mouse studies suggest inhibiting E. coli qseC could help treat Crohn’s disease and ulcerative colitis (UC). In an E. coli strain isolated from a patient...
07:00 , Sep 18, 2008 |  BC Innovations  |  Distillery Therapeutics

This Week in Therapeutics

This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Infectious disease Bacterial infection Sensor histidine kinase QseC Studies in cell culture and in mice suggest that inhibiting QseC signaling could be...
07:00 , Sep 18, 2008 |  BC Innovations  |  Targets & Mechanisms

Targeting bacterial virulence

Bacterial virulence factors are attractive therapeutic targets because they do not affect bacterial growth and thus should be under less selective pressure to develop drug resistance. One drawback, however, is that virulence factors are often...