...to report data from both ASTRAL-2 and ASTRAL-3 in mid-2020. Guadecitabine is a small molecule DNA methyltransferase... ...Product: Guadecitabine (formerly SGI-110) Business: Cancer Molecular target: DNA (cytosine-5-)-methyltransferase 1 (DNMT1) Description: Small molecule DNA methyltransferase...
...plus the CRISPR-Cas12a system designed to introduce mutations into hypoxanthine phosphoribosyltransferase 1 (HPRT1; HGPRT) or DNA methyltransferase... ...Li
Max Planck Institute for Evolutionary Anthropology
CRISPR from Prevotella and Francisella 1 (Cas12a) (Cpf1)
CRISPR-associated protein 9 (Cas9)
...develop EPI01 for oncology indications. EPI01 is an oral formulation of two small molecules -- DNA methyltransferase... ...Solon, Ohio Novo Nordisk A/S (CSE:NOVOB; NYSE:NVO), Bagsvaerd, Denmark Business: Hematology
Novo Nordisk A/S
Cytidine deaminase (CDA)