BioCentury | Mar 25, 2010
Distillery Therapeutics

Indication: Cancer

...Polymerase (DNA directed)-g (POLG); POLB In vitro studies suggest that inhibiting DNA polymerases POLG and POLB...
...seen when using control siRNA. In an MSH2-deficient colon cancer cell line, siRNA knockdown of POLB...
...siRNA treatment. Next steps include identifying an industry partner to develop inhibitors of POLG and POLB...
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