BioCentury | Feb 1, 2018
Translation in Brief

New Therapeutic Targets and Biomarkers: January 2018

...of TCRG on γδ T cells could help treat SCI. Jinan University Distillery Therapeutics Stroke Discs large homolog associated protein 4...
BioCentury | Jan 31, 2018
Distillery Therapeutics

Neurology

...Next steps could include optimizing the delivery of the DLGAP4 circRNA-expression vector. TARGET/MARKER/PATHWAY: MicroRNA-143 (miR-143); discs large homolog associated protein 4...
BioCentury | May 24, 2017
Distillery Techniques

Biomarkers

TECHNOLOGY: Gene profiling A panel of oncogenic gene fusions in tumors could provide new therapeutic targets for colorectal cancer. Transcriptome sequencing of stage I-III primary tumors and matched healthy colon tissue from 278 colorectal cancer...
BioCentury | Mar 3, 2016
Targets & Mechanisms

Rescue mission

A pair of preclinical studies published last month on the autism target SHANK3 provide what might be the most meaningful progress for patients since the gene was linked with the disease over a decade ago....
BioCentury | Jul 18, 2013
Distillery Therapeutics

Indication: Various

This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Various Obesity; obsessive compulsive disorder (OCD) Discs large homolog-associated protein 3 (DLGAP3; SAPAP3); melanocortin 4 receptor (MC4R); Mouse studies suggest inhibition of...
BioCentury | Jan 29, 2009
Distillery Therapeutics

Indication: Cancer

This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Adrenal cancer Budding uninhibited by benzimidazoles 1 homolog-b (BUB1B); discs, large homolog-associated protein 5 (DLGAP5; DLG7); PTEN-induced putative kinase 1 (PINK1)...
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