BioCentury | Feb 20, 2014
Distillery Techniques

Technology: Drug platforms

...protein p63 (TP63; p63) ΔNp63 isoform or DGCR8 microprocessor complex subunit (DGCR8) In vitro studies suggest depleting ΔNp63 or DGCR8...
...stem cells. In mouse or human epidermal cells, shRNA against or knockout of ΔNp63 and DGCR8...
...compared with control shRNA or no alteration and allowed differentiation into multiple cell types. Restoring DGCR8...
BioCentury | Jun 27, 2013
Distillery Therapeutics

Indication: Neurology

...restoring IGF-2 could help treat schizophrenia. In mice, knockout of DiGeorge syndrome chromosomal region 8 (Dgcr8...
BioCentury | Feb 3, 2007
Clinical News

DGCR8 essential for ES cell differentiation

...Researchers from the University of California, San Francisco, reported in Nature Genetics that DGCR8, a nuclear...
...binds to double-stranded RNA, is required for the biogenesis of microRNA (miRNA). The researchers created DGCR8-knockout...
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