08:00 , Feb 20, 2014 |  BC Innovations  |  Distillery Techniques

Technology: Drug platforms

Approach Summary Licensing status Publication and contact information Drug platforms Inducing multipotent progenitor cells from keratinocytes by depleting the tumor protein p63 (TP63; p63) ΔNp63 isoform or DGCR8 microprocessor complex subunit (DGCR8) In vitro studies...
07:00 , Jun 27, 2013 |  BC Innovations  |  Distillery Therapeutics

Indication: Neurology

This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Neurology Schizophrenia Insulin-like growth factor-2 (IGF-2); insulin-like growth factor-1 receptor (IGF1R; CD221) A mouse study suggests restoring IGF-2 could help treat schizophrenia....
03:56 , Feb 3, 2007 |  BC Extra  |  Clinical News

DGCR8 essential for ES cell differentiation

Researchers from the University of California, San Francisco, reported in Nature Genetics that DGCR8, a nuclear protein that binds to double-stranded RNA, is required for the biogenesis of microRNA (miRNA). The researchers created DGCR8-knockout murine...