BioCentury | Jan 9, 2014
Distillery Therapeutics

Indication: Cancer

...Deoxyhypusine hydroxylase/monooxygenase (DOHH) Studies in cell culture suggest antagonizing DOHH could be useful for treating cervical cancer. DOHH...
...eukaryotic translation initiation factor 5A (eIF5A), which promotes tumor growth. In human cancer cells, the DOHH...
BioCentury | Jun 10, 2010
Cover Story

Unique pathway in diabetes

...This conversion requires the sequential activity of two enzymes: deoxyhypusine synthase ( DHPS ) and deoxyhypusine hydroxylase/monooxygenase (DOHH)...
...to treat multiple myeloma (MM). Dondero said systemic inhibition of hypusination by targeting DHPS or DOHH...
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