BioCentury | Mar 31, 2016
Distillery Therapeutics

Therapeutics: Dehydrosqualene desaturase (CrtN)

...Infectious disease INDICATION: Staphylococcus In vitro, human blood and mouse studies identified a Naftin naftifine-derived CrtN...
...the enzymatic activity of CrtN with an IC50 of 338.8 nM in vitro and inhibited CrtN-mediated...
...compound decreased bacterial burden in the kidney, liver and/or heart. Next steps include testing the CrtN...
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