20:34 , May 23, 2017 |  BC Innovations  |  Distillery Therapeutics

Cancer

INDICATION: Brain cancer Cell culture and mouse studies suggest inhibiting DAXX could help treat PTEN -deficient glioblastoma multiforme (GBM). In PTEN-deficient neurospheres from patients, DAXX knockout decreased cell proliferation, self-renewal capacity and the number and...
19:08 , Jan 18, 2017 |  BC Innovations  |  Distillery Therapeutics

Cancer

INDICATION: Lung cancer Patient sample, cell culture and mouse studies suggest promoting DAXX expression could help treat lung cancer. In patients with non-small cell lung cancer (NSCLC) tumors that overexpressed the metastasis-promoting SNAI2 gene, low...
08:00 , Feb 24, 2011 |  BC Innovations  |  Distillery Therapeutics

Indication: Cancer

This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Pancreatic cancer; neuroendocrine tumors Multiple endocrine neoplasia I (MEN1; menin); death-domain associated protein (DAXX); a-thalassemia/mental retardation syndrome X-linked (ATRX); mammalian target...