BC Innovations | Feb 20, 2019
Distillery Therapeutics

Infectious disease

INDICATION: West Nile virus In vitro and cell culture studies identified a benzenesulfonamide-based DDX3X inhibitor that could help treat West Nile viral infection. Chemical synthesis and in vitro screening of analogs of a previously reported...
BC Innovations | Nov 2, 2018
Targets & Mechanisms

FDA’s pediatric target picks

FDA is looking ahead of industry in its guideline on targets for pediatric oncology, which includes more than 50 not yet in company pipelines in a list of over 220 the agency has its eye...
BC Innovations | Nov 15, 2016
Distillery Therapeutics

Cancer

INDICATION: Prostate cancer Cell culture and mouse studies suggest inhibiting DDX3 in combination with radiation treatment could help treat prostate cancer. In DDX3-expressing human prostate cancer cell lines, shRNA targeting DDX3 or a DDX inhibitor...
BC Innovations | Aug 2, 2012
Distillery Techniques

Technology: Markers

Approach Summary Licensing status Publication and contact information Markers Subtype-specific somatic mutations in medulloblastoma Identification of new subtype-specific somatic mutations in medulloblastoma could aid the development of new treatments for the disease. Whole-exome hybrid capture...
BC Innovations | Aug 21, 2008
Distillery Therapeutics

This Week in Therapeutics

This week in therapeutics Indication Target/marker/ pathway Summary Licensing status Publication and contact information Infectious disease HIV/AIDS Ring-expanded nucleosides; DEAD box polypeptide 3 (DDX3) Studies in cell culture and in mice identified ring-expanded nucleoside analogs...
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