07:00 , Aug 4, 2011 |  BC Innovations  |  Tools & Techniques

Metabolically, man or mouse

Massachusetts researchers have created mice withhuman ectopic artificial livers that were used to evaluate human drug metabolism, drug-drug interactions and drug-induced liver injuryin a proof-of-principle study.1 Unlike animal models that are currently under development for...
07:00 , Mar 12, 2007 |  BC Week In Review  |  Company News

CXR, Millipore sales and marketing update

MIL and co-development partner CXR launched collections of anti-bodies that identify human enzymes and trancription factors involved in drug metabolism and regulation. The antibodies recognize cytochrome P450 2D6 (CYP2D6), cytochrome P450 2A6 (CYP2A6);...
07:00 , Jun 29, 1998 |  BC Week In Review  |  Company News

University of Toronto other research news

Canadian researchers published in Nature a genetic variation in an enzyme responsible for breaking down nicotine. Individuals who lack a fully functional enzyme that changes nicotine to cotinine may be protected against nicotine addiction. The...