BC Innovations | Aug 6, 2015
Distillery Therapeutics

Therapeutics: Cysteine-rich angiogenic inducer 61 (CYR61; CCN1)

Dermatology INDICATION: Wounds Mouse studies suggest CYR61 could promote wound healing. Normal wound healing depends on CYR61-mediated recognition of apoptotic markers on neutrophils by integrin α5 ( CD49e ) on macrophages, followed by macrophage-mediated neutrophil clearance. In...
BC Innovations | Aug 8, 2013
Distillery Therapeutics

Indication: Ophthalmic disease

Indication Target/marker/pathway Summary Licensing status Publication and contact information Ophthalmic disease Diabetic retinopathy Cysteine-rich angiogenic inducer 61 (CYR61; CCN1) Patient and mouse studies suggest targeting CCN1 and its degradation products could help treat proliferative diabetic...
BC Innovations | Dec 1, 2011
Distillery Therapeutics

Indication: Cancer

Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Breast cancer Cysteine-rich angiogenic inducer 61 (CYR61); sonic hedgehog homolog (SHH) Mouse studies suggest inhibiting CYR61 could help treat SHH-driven breast cancer. In a mouse...
Items per page:
1 - 3 of 3