07:00 , Aug 6, 2015 |  BC Innovations  |  Distillery Therapeutics

Therapeutics: Cysteine-rich angiogenic inducer 61 (CYR61; CCN1)

Dermatology INDICATION: Wounds Mouse studies suggest CYR61 could promote wound healing. Normal wound healing depends on CYR61-mediated recognition of apoptotic markers on neutrophils by integrin α5 (CD49e) on macrophages, followed by macrophage-mediated neutrophil clearance. In wounded mice,...
07:00 , Aug 8, 2013 |  BC Innovations  |  Distillery Therapeutics

Indication: Ophthalmic disease

Indication Target/marker/pathway Summary Licensing status Publication and contact information Ophthalmic disease Diabetic retinopathy Cysteine-rich angiogenic inducer 61 (CYR61; CCN1) Patient and mouse studies suggest targeting CCN1 and...
08:00 , Dec 1, 2011 |  BC Innovations  |  Distillery Therapeutics

Indication: Cancer

Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Breast cancer Cysteine-rich angiogenic inducer 61 (CYR61); sonic hedgehog homolog (SHH) Mouse studies suggest inhibiting CYR61 could...