20:01 , Feb 1, 2018 |  BC Innovations  |  Translation in Brief

New Therapeutic Targets and Biomarkers: January 2018

New Therapeutic Targets and Biomarkers: January 2018 Select top therapeutic targets and biomarkers covered by BioCentury or added to the BCIQ database during January 2018. Therapeutic targets are defined as any protein, gene or other molecule...
21:17 , Jan 23, 2018 |  BC Innovations  |  Distillery Therapeutics

Cancer

INDICATION: Liver cancer Cell culture and mouse studies suggest inhibiting CCNE1 and CCNE2 could help treat liver cancer. In human liver cancer cell lines, combined shRNA-mediated knockdown of CCNE1 and CCNE2 decreased proliferation and colony formation...
07:00 , Jul 22, 2010 |  BC Innovations  |  Targets & Mechanisms

Suppressing cancer with miR-34a

A team of researchers at Mirna Therapeutics Inc. has found that systemically delivered microRNA-34a blocks tumor growth in mouse models of lung cancer.1 The miRNA targets multiple pro-oncogenic pathways and could potentially show activity against...