BioCentury | Apr 17, 2019
Preclinical News

Atomwise unveils Chagas disease compounds from AIMS program

...Heifets told BioCentury that DNDi has identified six small molecules with single-digit μM potencies against cruzain...
...proposals from academics and non-profit researchers for the AIMS program until April 29. Targets: Cruzain (cruzipain...
...Trypanosoma peroxin 14 Sandi Wong, Staff Writer Atomwise Inc. Drugs for Neglected Diseases initiative (DNDi) University of Connecticut Cruzain (cruzipain) Glyceraldehyde-3-phosphate...
BioCentury | May 15, 2008
Distillery Therapeutics

This Week in Therapeutics

...a small molecule irreversible inhibitor of cruzain that may be useful for treating Chagas disease. Cruzain...
...include testing the compound in animal models of Chagas disease. Patent pending for nonpeptidic irreversible cruzain...
BioCentury | Jul 7, 1997
Company News

ArQule, University of California deal

...design of protease inhibitors, initially targeting Kaposi's sarcoma, herpes virus, a Chagas disease protease called cruzain...
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