21:45 , Jul 10, 2018 |  BC Innovations  |  Distillery Techniques

Drug delivery

TECHNOLOGY: Nanoparticles Gold-based nanoparticles could be used to deliver CRISPR-Cas9 and CRISPR-Cas12a constructs for neurological diseases. The nanoparticles are generated by conjugating gold nanoparticles to DNA oligonucleotides that bind to the CRISPR endonuclease and single-guide...
23:00 , Jun 25, 2018 |  BC Extra  |  Preclinical News

Brain-targeted CRISPR could treat autism behaviors

Researchers at University of Texas Health Science Center, University of California Berkeley and GenEdit Inc. (Berkeley, Calif.) used gold nanoparticles as a non-viral method to deliver the CRISPR gene editing complex into the brain and...
19:23 , Jun 20, 2018 |  BC Innovations  |  Distillery Techniques

Drug platforms

TECHNOLOGY: Gene therapy A four-compound cocktail could enhance the efficiency of CRISPR-based editing in pluripotent stem cells. The method involves CRISPR-based editing in pluripotent stem cells with systems based on CRISPR from Prevotella and Francisella 1...