BioCentury | Dec 11, 2018
Distillery Therapeutics

Cardiovascular

...under hypoxic conditions yielded a pyrimidinone-based compound that decreased levels of the myocardial injury markers creatine kinase MB...
...In a mouse model of MI, the compound decreased infarct size and serum levels of creatine kinase MB...
BioCentury | Sep 5, 2016
Clinical News

CAP-1002: Preliminary Phase I data

...prolongs hospitalization, development of or increased frequency of ventricular tachycardia, antibodies and peak troponin and creatine kinase MB...
BioCentury | Apr 6, 2015
Clinical News

IV Bendavia: Phase II data

...to a lower AUC for creatine kinase MB vs. placebo (5,570 vs. 5,785 ng*h/mL). Stealth BioTherapeutics said creatine kinase MB...
...an enzyme used to estimate cardiac damage from a myocardial infarction (MI). Maximum levels of creatine kinase MB...
...syndrome (ACS) Endpoint: Myocardial infarct size as measured by area under the curve (AUC) for creatine kinase MB...
BioCentury | Mar 18, 2013
Clinical News

Inclacumab: Phase II data

...hours of 33.9% (p=0.08). Additionally, inclacumab led to placebo-adjusted geometric mean reductions from baseline in creatine kinase MB...
...post-PCI (p=0.06). Furthermore, a significantly smaller proportion of patients receiving inclacumab had an increase in creatine kinase MB...
...24 hours post-PCI; peak and area under the curve (AUC) for cardiac troponin I levels, creatine kinase MB...
BioCentury | Jul 16, 2012
Company News

Alere sales and marketing update

...in effect prior to the inspection." CardioProfiler is an immunoassay which measures the troponin I, creatine kinase MB...
...B-type natriuretic peptide (BNP) cardiac markers in whole blood and plasma, while Cardiac Panel measures creatine kinase MB...
BioCentury | Jul 4, 2011
Clinical News

CMX-2043: Phase IIa data

...intervention (PCI) Endpoint: Safety; efficacy based on changes observed in biomarkers of cardiac injury, including creatine kinase MB...
BioCentury | Sep 27, 2010
Company News

Roche sales and marketing update

...use on its cobas 6000 analyzer. The new 9-minute assays include troponin T, troponin I, creatine kinase MB...
BioCentury | Mar 15, 2010
Clinical News

CMX-2043: Phase IIa started

...peri-operative Ischemia/reperfusion injury in patients undergoing PCI procedures Endpoint: Safety as measured by changes in creatine kinase MB...
BioCentury | Nov 23, 2009
Clinical News

Serp-1: Phase IIa data

...adverse events. VT-111 also significantly reduced levels of the cardiac damage biomarkers troponin I and creatine kinase MB...
BioCentury | May 11, 2009
Company News

Inverness sales and marketing update

...diagnose myocardial infarction. Biosite said quality control testing of the lot showed low recovery of creatine kinase MB...
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