BioCentury | Aug 18, 2018
Regulation

Pediatric push

...2017, and Vimpat lacosamide, an enhancer of sodium channel inactivation and modulator of collapsin response mediator protein-2 (DPYSL2; CRMP-2...
BioCentury | Apr 27, 2018
Company News

UCB buys rights to seizure candidate

...SV2A) ligand, while Vimpat selectively enhances slow inactivation of sodium channels and modulates collapsin response mediator protein-2 (DPYSL2; CRMP-2...
BioCentury | Apr 20, 2018
Company News

UCB buys rights to seizure candidate

...SV2A) ligand, while Vimpat selectively enhances slow inactivation of sodium channels and modulates collapsin response mediator protein-2 (DPYSL2; CRMP-2). Elizabeth...
BioCentury | Apr 6, 2018
Preclinical News

New life for Toyama compound in brain damage recovery

...A paper in Science suggests collapsin response mediator protein-2 (DPYSL2; CRMP-2)-binding small molecule edonerpic maleate (T-817MA), which missed the...
...retrieval compared with vehicle throughout rehabilitation (p<0.001). Jaime De Leon T-817MA Fujifilm Holdings Corp. Toyama Chemical Co. Ltd. Yokohama City University Collapsin response mediator protein-2 (DPYSL2) (CRMP-2) edonerpic...
BioCentury | May 12, 2017
Company News

Adamas, HCR in $100M royalty deal

...ADS-4101 , an extended-release formulation of the anticonvulsant lacosamide, which targets collapsin response mediator protein-2 ( DPYSL2 ; CRMP-2...
BioCentury | May 11, 2017
Financial News

Adamas, HCR in $100M royalty deal

...ADS-4101 , an extended-release formulation of the anticonvulsant lacosamide, which targets collapsin response mediator protein-2 ( DPYSL2 ; CRMP-2...
BioCentury | May 9, 2017
Clinical News

CRMP-2 tied to lithium response in bipolar disorder

...researchers from the Sanford Burnham Prebys Medical Discovery Institute showed that collapsin response mediator protein-2 ( DPYSL2 ; CRMP-2...
...iPS) cells from patients with bipolar disorder, the authors showed that lithium lowers phosphorylation of CRMP-2...
...In brains of bipolar disorder patients not treated with lithium, the authors found increased phosphorylated CRMP-2...
BioCentury | Dec 22, 2016
Clinical News

Vimpat regulatory update

...anticonvulsant that selectively enhances slow inactivation of sodium channels and modulates collapsin response mediator protein-2 ( DPYSL2 ; CRMP-2...
...DPYSL2 ; CRMP-2). UCB Group (Euronext:UCB), Brussels, Belgium Product: Vimpat lacosamide Business: Neurology Julian Zhu lacosamide Vimpat UCB Group Collapsin response mediator protein-2 (DPYSL2) (CRMP-2)...
BioCentury | Nov 14, 2016
Clinical News

Vimpat regulatory update

...anticonvulsant that selectively enhances slow inactivation of sodium channels and modulates collapsin response mediator protein-2 ( DPYSL2 ; CRMP-2...
...DPYSL2 ; CRMP-2). UCB Group (Euronext:UCB), Brussels, Belgium Product: Vimpat lacosamide Business: Neurology Julian Zhu lacosamide Vimpat UCB Group Collapsin response mediator protein-2 (DPYSL2) (CRMP-2)...
BioCentury | Sep 5, 2016
Company News

UCB, Daiichi Sankyo sales and marketing update

...anticonvulsant that selectively enhances slow inactivation of sodium channels and modulates collapsin response mediator protein-2 ( DPYSL2 ; CRMP-2...
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