23:26 , Jul 25, 2019 |  BC Innovations  |  Distillery Therapeutics

Inhibiting CAPN9 to treat fibrosis

DISEASE CATEGORY: Pulmonary; hepatic; cardiovascular INDICATION: Pulmonary fibrosis; liver fibrosis; cardiac fibrosis Inhibition of CAPN9 could treat fibrosis by blocking a TGFβ-induced pathway that contributes to fibrosis development. Two tool compound CAPN9 inhibitors decreased TGFβ-induced...
21:03 , Jan 30, 2019 |  BC Innovations  |  Translation in Brief

Epigenetic links in endometriosis

An HDAC3-mediated epigenetic pathway could lead to new therapies and markers for endometriosis and associated infertility. Researchers from Michigan State University and Yonsei University College of Medicine have linked an epigenetic pathway involving HDAC3 to...
07:00 , Mar 20, 2008 |  BC Innovations  |  Markers

Micro Management

In the past four years, at least two biotechs have released tests that use mRNA-based gene signatures to predict the likelihood of breast cancer recurrence. Now, research is emerging that suggests microRNAs could also have...
07:00 , Jul 2, 2001 |  BC Week In Review  |  Company News

Axis-Shield, Gemini Genomics, Specialty Laboratories Inc. sales and marketing update

GMNI said that marketing and development partner ASD granted SP exclusive U.S. rights to a gene-based osteoporosis screening test based on GMNI's patent on the type 1 collagen ( COL1A1 ) gene. SP expects to...