08:00 , Feb 19, 2009 |  BC Innovations  |  Distillery Therapeutics

Indication: Cancer

This week in therapeutics Indication Target/ marker/pathway Summary Licensing status Publication and contact information Cancer Ovarian cancer Claudin 3 (CLDN3) Studies in mice suggest that small interfering RNA silencing of CLDN3 may help treat ovarian...
08:00 , Feb 16, 2009 |  BC Week In Review  |  Clinical News

Alnylam preclinical data

Data published in Proceedings of the National Academy of Sciences showed that lipidoid-formulated siRNA against claudin 3 (CLDN3) reduced tumor growth and metastases in 3 different mouse tumor models of ovarian cancer. In a xenograft...