01:29 , Feb 28, 2019 |  BC Innovations  |  Distillery Therapeutics

Infectious disease

INDICATION: Encephalitis Mouse studies suggest inhibiting CMA1 could help treat Japanese encephalitis (JE). In mice non-lethally infected with JE virus, serum levels of a mouse homolog of CMA1 were higher after infection with JE virus...
07:00 , Apr 8, 2010 |  BC Innovations  |  Distillery Therapeutics

Indication: Cardiovascular disease

Indication Target/marker/pathway Summary Licensing status Publication and contact information Cardiovascular disease Heart failure Chymase 1 mast cell (CMA1); angiotensin-converting enzyme (ACE) Studies in rodents suggest that dual CMA1 and ACE inhibitors could help treat heart...